Acyl bromides
Medchemexpress LLC Valethamate (bromide) | 90-22-2 | 99.3% | 1 ML
Valethamate bromide is an ester that acts as an effective, rapidly acting anticholinergic antispasmodic and muscle relaxant. It accelerates labor by improving cervical dilation, significantly shortening the labor process with fewer side effects.
- Acts as an effective, rapidly acting anticholinergic antispasmodic and muscle relaxant
- Accelerates labor by improving cervical dilation
- Significantly shortens the labor process with fewer side effects
- For research use only
Medchemexpress LLC N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite | 179479-02-8 | 98.0% | C48H54N7O8P | 50 MG
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog primarily functioning as a smooth muscle vasodilator. It has also shown properties in inhibiting cancer progression, making it relevant for research in various disease areas.
- Acts as a smooth muscle vasodilator
- Inhibits cancer progression
- Useful in research for cancer, cardiovascular disease, and blood diseases
- For research use only
Medchemexpress LLC Demecarium bromide | 56-94-0 | 95.0% | 1 ML
Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor known for its apparent affinity (Kiapp) of 0.15 μM. It serves as a glaucoma agent, effective in both normotensive and inherited glaucoma conditions. In vivo studies demonstrate its ability to cause long-term miosis and decrease intraocular pressure.
- Potent cholinesterase inhibitor
- Apparent affinity (Kiapp) of 0.15 μM
- Used as a glaucoma agent
- Causes long-term miosis
- Decreases intraocular pressure (IOP)
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 50MG
Fentonium bromide | 5868-06-4 | 98.8% | 50MG
TARGETMOL CHEMICALS INC Pipecuronium bromide 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics. Purity 100%
Medchemexpress LLC 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine | 51549-36-1 | 98.0% | 445.58 | 10 MM X 1 ML
5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside suitable for use in the synthesis of deoxyribonucleic acid or nucleic acid.
- Modified nucleoside for various research applications
- Purity of 98.0%
- Available as a white to off-white solid
- Stable under recommended storage conditions
- Soluble in DMSO at 250 mg/mL
Medchemexpress LLC Aclidinium Bromide | 320345-99-1 | 98.96% | C₂₆H₃₀BrNO₄S₂ | 25 MG
Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist with potential for research related to chronic obstructive pulmonary disease (COPD). It shows potent antagonism of human muscarinic receptors and is rapidly hydrolyzed in human plasma.
- Potent antagonism of human muscarinic receptors
- Long residence time at M3 receptors and a shorter residence time at M2 receptors
- Suggests sustained bronchodilation
- Rapid hydrolysis in human plasma
- Low systemic bioavailability and favorable safety profile in early clinical studies
Medchemexpress LLC Sofpironium bromide | 1628106-94-4 | 98.26% | 470.40 | 50 MG
Sofpironium bromide is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). It reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site and also has a high affinity for the M1, M2, M4, and M5 subtypes. Sofpironium bromide is metabolized mainly through non-enzymatic hydrolysis, and also through oxidative metabolism via CYP2D6 and CYP3A4. In a rat model, it reduces footpad sweating induced by Pilocarpine (a muscarinic receptor agonist). It exhibits anticholinergic activity by inhibiting the contractile activity of guinea pig ileal tissue in a concentration-dependent manner.
- Reduces sweating by inhibiting M3 muscarinic receptors
- High affinity for M1, M2, M4, and M5 muscarinic receptor subtypes
- Metabolized mainly through non-enzymatic hydrolysis
- Exhibits anticholinergic activity
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 100 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and the subsequent opening of the ligand-gated ion channel. It is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). It has also been shown to improve symptoms of COPD complicated by chronic heart failure.
- Muscarinic acetylcholine receptor (mAChR) antagonist
- Blocks binding of acetylcholine ligand and opening of ligand-gated ion channel
- Stops signaling between neurons leading to muscle relaxation
- Long-acting, 24-hour anticholinergic bronchodilator
- Used in the management of chronic obstructive pulmonary disease (COPD)
- Improves symptoms of COPD complicated by chronic heart failure
- For research use only
Medchemexpress LLC Rocuronium Bromide | 119302-91-9 | ≥95% | 609.68 | 100 MG
Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant. It is used in modern anaesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
- Reduced twitch tensions in normal and pretreated diaphragms in a concentration-dependent fashion.
- ED95 is similar for children and adults.
- Duration of action is similar to vecuronium, shorter for children than adults.
- Readily reversed with conventional doses of cholinesterase-inhibiting drugs.
- Facilitates endotracheal intubation.
- Provides skeletal muscle relaxation during surgery or mechanical ventilation.
Medchemexpress LLC Rocuronium Bromide (ORG 9426 Bromide) | 119302-91-9 | 98.0% | 609.68 | 5 MG
Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is intended for research use only.
- Aminosteroid non-depolarizing neuromuscular blocker
- Muscle relaxant
- Used in modern anaesthesia
- Facilitates endotracheal intubation
- Provides skeletal muscle relaxation during surgery or mechanical ventilation
- For research use only
![Medchemexpress LLC Piperidinium, 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethyl-, bromide (1:1) | 76-90-4 | 99.9% | 420.34 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387143-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Piperidinium, 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethyl-, bromide (1:1) | 76-90-4 | 99.9% | 420.34 | 1 ML
Mepenzolate bromide is an orally administered muscarinic receptor antagonist, with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. It can be used to suppress gastrointestinal hypermotility associated with irritable bowel syndrome, and is also identified as a GPR109A inhibitor.
- Orally administered muscarinic receptor antagonist
- Suppresses gastrointestinal hypermotility
- Effective against irritable bowel syndrome
- Functions as a GPR109A inhibitor
Medchemexpress LLC Domiphen bromide | 538-71-6 | 98.7% | 5 G
Domiphen bromide | 538-71-6 | 98.7% | 5 G